Payal chopra biography sample
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Abstract
Acquiring the recommended daily allowance of vitamins is crucial for maintaining homeostatic balance in humans and other animals. A deficiency in or dysregulation of vitamins adversely affects the neuronal metabolism, which may lead to neurodegenerative diseases. In this article, we discuss how novel vitamin-based approaches aid in attenuating abnormal neuronal functioning in neurodegeneration-based brain diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, Amyotrophic lateral sclerosis, and Prion disease. Vitamins show their therapeutic activity in Parkinson’s disease by antioxidative and anti-inflammatory activity. In addition, different water- and lipid-soluble vitamins have also prevented amyloid beta and tau pathology. On the other hand, some results also show no correlation between vitamin action and the prevention of neurodegenerative diseases. Some vitamins also exhibit toxic activity too. This review discusses both the beneficial and null effects of vitamin supplementation for neurological disorders. The detailed mechanism of action of both water- and lipid-soluble vitamins is addressed in the manuscript. Hormesis is also an essential factor that is very helpful to determine the effective dose of vitamins. PubMed, Google Scholar,
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Rajesh Khanna
Indian actor, film producer and politician (1942–2012)
Rajesh Khanna (pronounced[rɑːˈdʒeːʃkʰənˈnə]) (pronunciationⓘ; born Jatin Khanna; 29 December 1942 – 18 July 2012) was an Indian actor, film producer and politician who worked in Hindi films. Considered as one of the greatest and most successful actors in the history of Indian cinema, he is known as the first Superstar of Hindi cinema.[5][6]His accolades include five Filmfare Awards, and in 2013, he was posthumously awarded the Padma Bhushan, India's third highest civilian honour.
Khanna made his debut in 1966 Aakhri Khat which was India's first official Academy Awards entry in 1967.[7] In 2005, he was honoured with the Filmfare Lifetime Achievement Award on the 50th anniversary of the Filmfare Awards.[8][9] He was a Member of Parliament in the 10th Lok Sabha from New Delhi Lok Sabha constituency between 1992 and 1996, elected in the 1992 New Delhi by-election as an Indian National Congress candidate.[10]
He married Dimple Kapadia in March 1973, eight months before her debut film Bobby was released and had two daughters from the marriage. Their elder daughter Twinkle Khanna is a former actress married to actor Akshay Kumar,
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